国家神经系统疾病临床医学研究中心数据管理与共享系统

Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases

Portable near-infrared rapid detection of intracranial hemorrhage in Chinese population

第一作者:Xu, Long

通讯作者:Zhao, Jizong

Intracranial hemorrhage NIR Near infrared TBI Tra

基本信息

  • 负责人:Xu, Long
  • 数据来源: OTHERS
  • 论文编号:OTHERS20190591
  • 发表时间:2017-06-01

2017-06-01

已发表文章

发表杂志:Journal of Clinical Neuroscience

发表类型: Research Article

影响因子(IF): 1.961

PMID: 28279553 Pubmed原文链接 全文下载

主要研究背景及目的

方法

Data was collected using the NIR device at the time of a computed tomography (CT) or magnetic resonance imaging (MRI) scan was performed to evaluate a suspected TBI. 85 patients were included in the per protocol population. Of the 85 patients, 45 were determined by CT scan to have intracranial hemorrhage. The CT and MRI scans were read by an independent neuroradiologist who was blinded to the NIR measurements.

结论

These results confirm in Chinese population the results of previous studies that demonstrated a NIR based device can reliably screen for intracranial hematomas that are likely to be of clinical importance.

主要结果

The NIR device demonstrated sensitivity of 95.6% (95% confidence intervals [CI] 83.6-99.2%) and specificity of 92.5% (CI 78.5-98%) in detecting intracranial hematomas larger than 3.5ml in volume, and that were less than 2.5cm from the surface of the brain.