国家神经系统疾病临床医学研究中心数据管理与共享系统

Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases

《国家中心数据管理与共享系统操作说明书 —— 研究者部分》

Association between marriage and outcomes in patients with acute ischemic stroke

第一作者：Liu Qi, QiWang Xianwei

通讯作者：Guo Li,Wang Yongjun

Acute ischemic stroke All-cause death Marital stat

基本信息

2018-04-01

已发表文章

发表杂志：J Neurol

发表类型: Original Communication

影响因子(IF): 4.849

PMID: 29464375 Pubmed原文链接 全文下载

主要研究背景及目的

方法

This was a multicenter, prospective cohort study of patients with AIS. Patients were classified into two groups based on marital status at admission: married and unmarried. The primary outcomes included all-cause mortality, stroke recurrence, combined endpoint, and stroke disability. Stroke disability was defined as modified Rankin Scale of 2-6.

结论

Marital status was associated with all adverse stroke outcomes in patients with acute ischemic stroke, especially in those with middle-school education.

主要结果

Of 12,118 patients, 1220 were unmarried and 10,898 married. Unmarried patients had higher proportion of 1-year post-stroke events than married patients did. As compared with being unmarried, the adjusted odds ratios with 95% confidence interval of being married for outcomes were as follows: 0.70 (0.58-0.84) for all-cause mortality, 0.78 (0.66-0.91) for stroke recurrence, 0.77 (0.66-0.90) for combined endpoint, and 0.75 (0.65-0.88) for stroke disability. Interactions between marital status and education were significant for all outcomes except for stroke disability.