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Encephaloduroarteriosynangiosis for pediatric moyamoya disease: a single-center experience with 67 cases in China

First author:Wang Chengjun, Chengjun

Corresponding author:Zhao Jizong, Jizong

Encephaloduroarteriosynangiosis indirect revascula

essential_information

2018-12-01

Published articles

Journal:J Child Neurol

Publication type: Article

IF(IF): 1.987

PMID: 30246586 Link To Pubmed Full text Download

Background And Purpose

Method

We performed a retrospective analysis of 67 pediatric patients with moyamoya disease who underwent encephaloduroarteriosynangiosis in Beijing Tiantan Hospital. The case series included 36 boys and 31 girls. All the patients underwent surgical revascularization, and a total of 93 encephaloduroarteriosynangiosis procedures were performed (41 unilateral, 26 bilateral). The mean follow-up period after surgery was 30 months.

Conclusion

Our study suggests that long-term surgical outcome of encephaloduroarteriosynangiosis in pediatric moyamoya disease patients is satisfactory, and this technique has a positive impact on the prevention of stroke recurrence.

Main results

During follow-up, ischemic stroke events were detected in 5 patients and the stroke rate for pediatric patients who underwent encephaloduroarteriosynangiosis procedure was 7.1% per patient-years. At the last follow-up, favorable outcomes (modified Rankin Scale score ≤ 2) were observed in 65 cases (97.0%).