国家神经系统疾病临床医学研究中心数据管理与共享系统

Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases

Lacunar infarction in adult patients with moyamoya disease

第一作者:ZhaoMeng, Meng

通讯作者:Zhao Jizong, Jizong

Lacunar infarction Moyamoya disease Revascularizat

基本信息

  • 负责人:ZhaoMeng, Meng
  • 数据来源: OTHERS
  • 论文编号:OTHERS20190759
  • 发表时间:2018-01-01

2018-01-01

已发表文章

发表杂志:Clinical Neurology and Neurosurgery

发表类型: Article

影响因子(IF): 1.876

PMID: 29202378 Pubmed原文链接 全文下载

主要研究背景及目的

方法

We reviewed 696 consecutive moyamoya patients admitted to our hospital from 2009 to 2015 to identify patients with lacunar infarctions. We compared the clinical features and prognosis of adult moyamoya patients with lacunar infarction and those with non-lacunar infarction. Follow-up was conducted by face-to-face reviews or by a structured telephone interview. Outcome measures were recurrent stroke events and functional outcomes by modified Rankin Scale (mRS).

结论

We identified that the moyamoya patients with lacunar infarctions had better functional outcomes comparing with patients with non-lacunar infarction after revascularization.

主要结果

We identified 32 patients with lacunar infarction among 197 adult moyamoya disease patients with infarctions. Patients with lacunar infarctions demonstrated similar angiographic features with patients with non-lacunar infarctions. During a mean follow-up of 33.02±20.49months, we observed recurrent stroke events in 1 patients with lacunar infarction and 14 patients with non-lacunar infarction. The mean follow-up mRS was significantly better in the lacunar group than in the non-lacunar group (0.59±0.56 vs. 1.13±1.24; P<0.001).