Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases
Tissue window, not the time window, will guide acute stroke treatment
First author：Wang David
Corresponding author：Wang David
essential_information
- Person in charge：Wang David
- Data Sources： OTHERS
- Number of papers：OTHERS20190877
- Published time：2019-02-11
2019-02-11
Published articles
Journal：Stroke and vascular neurology
Publication type: Editorial
IF(IF): 4.081
PMID: 31105971 Link To Pubmed Full text Download
Background And Purpose
Method
Recently two published clinical trials have used MRI mismatch rather than CT perfu- sion mismatch to guide the use of IV tPA up to patients with AIS between 6 and 12 hours of onset and the outcome was positive.
Conclusion
In the near future, artificial intelligence may help assess the presence of a penumbra faster and with more precision. Furthermore, a perfu- sion scan or MRI/T2WI should be done regard- less of the time of onset, be it within 3 hours or great than 24 hours onset, so that every patient with a stroke will have an accurate assessment of the tissue window, regardless of the time window.