Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases
Implementation and Outcome of Thrombolysis with Alteplase 3 to 4.5 h After Acute Stroke in Chinese Patients
First author：Xiaoling Liao,Chunxue Wang
Corresponding author：Yongjun Wang
essential_information
- Person in charge：Xiaoling Liao,Chunxue Wang
- Data Sources： TIMS-CHINA
- Number of papers：TIMS-CHINA20150128
- Published time：2013-01-10
2013-01-10
Published articles
Journal：CNS Neuroscience & Therapeutics
Publication type: Original Contributions
IF(IF): 5.243
PMID: 23206165 Link To Pubmed Full text Download
Background And Purpose
The European Cooperative Acute Stroke Study (ECASS) III showed that intravenous recombinant tissue plasminogen activator (rtPA) administered in the 3 to 4.5 h after symptom onset significantly improved clinical outcomes in patients with acute ischemic stroke (AIS). But little is known regarding the safety and efficacy of intravenous rtPA treatment within this extended time window in Chinese patients with AIS.