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Serum bilirubin levels are associated with poor functional outcomes in patients with acute ischemic stroke or transient ischemic attack

First author:Quping Ouyang,Anxin Wang

Corresponding author:Yongjun Wang

Bilirubin Prognosis Poor functional outcomes Acute ischemic stroke Transient ischemic attack

essential_information

2021-09-27

Published articles

Journal:BMC Neurology

Publication type: Original Contributions

IF(IF): 2.474

PMID: 34610800 Link To Pubmed Full text Download

Background And Purpose

The prognostic value of serum bilirubin in stroke is controversial since bilirubin has both neuroprotective and neurotoxic properties. We aimed to investigate the association between serum bilirubin, including total bilirubin (TBIL), direct bilirubin (DBIL) and indirect bilirubin (IBIL) and poor functional outcomes in patients with acute ischemic stroke (AIS) or transient ischemic attack (TIA).

Method

Multivariable logistic regression.

Conclusion

Elevated levels of serum bilirubin were significantly associated with poor functional outcomes in patients with AIS or TIA at 3 months and 1 year.

Main results