Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases
Emerging malnutrition during hospitalisation independently predicts poor 3-month outcomes after acute stroke: data from a Chinese cohort
First author：Jing Zhang
Corresponding author：Yongjun Wang
essential_information
- Person in charge：Jing Zhang
- Data Sources： OTHERS
- Number of papers：OTHERS20190158
- Published time：2015-09-02
2015-09-02
Published articles
Journal：Asia Pacific Journal of Clinical Nutrition
Publication type: Original Contributions
IF(IF): 1.662
PMID: 26420177 Link To Pubmed Full text Download
Background And Purpose
Questions exist regarding the causal relationship between malnutrition and stroke outcomes. This study aimed to determine whether nutritional status changes or malnutrition during hospitalisation could predict 3-month outcomes in acute stroke patients.
Method
During a 10-month period, patients who suffered their first stroke within 7 days after stroke onset were included in this prospective multi-centre study. The demographic parameters, stroke risk and severity factors, malnutrition risk factors and dysphagia were recorded. Nutritional status was assessed by 3 anthropometric and 3 biochemical indices. Changes in nutritional status were defined by comparing the admission values with the 2-week values. A Modified Rankin Scale score of 3-6 was defined as a poor outcome at the 3-month follow-up. Univariate and multiple logistic regression analyses were used to investigate the power of nutritional status changes in predicting poor patient outcomes.
Conclusion
Emerging malnutrition during hospitalisation independently predicted poor 3-month outcomes in acute stroke patients in this study.
Main results
Data from 760 patients were analysed. Poor outcomes were observed in 264 (34.7%) patients. Malnutrition prevalence was 3.8% at admission and 7.5% after 2-weeks in hospital, which could not predict 3-month outcome. Emerging malnutrition was observed in 36 patients (4.7%) during the 2-week hospitalisation period and independently predicted poor 3- month outcomes after adjusting for confounding factors (odds ratio 1.37, 95% confidence interval, 1.03-1.83)