国家神经系统疾病临床医学研究中心数据管理与共享系统
Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases
Importance of an adequately performed Valsalva maneuver for detecting a right-to-left shunt indicating foramen ovale reopening
第一作者：Dongmei Wei
通讯作者：Yi Ju
基本信息
- 负责人：Dongmei Wei
- 数据来源： OTHERS
- 论文编号：OTHERS20190355
- 发表时间：2015-05-01
2015-05-01
已发表文章
发表杂志：Journal of Ultrasound in Medicine
发表类型: Original Research
影响因子(IF): 2.153
PMID: 25911721 Pubmed原文链接 全文下载
主要研究背景及目的
方法
We prospectively analyzed 260 patients (102 women and 158 men; mean age ± SD, 41 ± 19 years; range, 13-83 years) who underwent transesophageal echocardiography and agitated saline injection. Two-dimensional echocardiography, color Doppler imaging, and microbubbles were used to detect right-to-left shunts, and the Valsalva maneuver was performed to determine whether the functional closure of the foramen ovale had reopened.
结论
An adequately performed Valsalva maneuver is important for detecting a right-to-left shunt indicating reopening of the functional closure of the foramen ovale.
主要结果
Transesophageal echocardiography with color Doppler imaging identified a patent foramen ovale in 20 patients: 18 patients with a patent foramen ovale had left-to-right shunts, and 2 patients with atrial septal defects had bidirectional shunts. Both patients with atrial septal defects showed right-to-left shunt microbubbles without and with the Valsalva maneuver, whereas all 18 patients with a patent foramen ovale showed right-to-left shunt microbubbles only after the Valsalva maneuver. Foramen ovale reopening was identified by transesophageal echocardiography in an additional 40 patients with no shunt during rest on agitated saline injection and in whom the right-to-left shunt appeared only after the Valsalva maneuver. The Valsalva maneuver could cause an atrial septal swing, and its sensitivity and specificity were 100%.