Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases

Journal：J Neurosurg

Publication type: Research Article

IF(IF): 5.115

PMID: 26544772 Link To Pubmed Full text Download

MR images of 15 patients with ischemic-type MMD (8 males, 7 females; age 13–48 years) and 13 healthy  controls (7 males, 6 females; age 19–28 years) who underwent both 7.0-T and 3.0-T MRI and MRA were studied retrospectively. The main intracranial arteries were assessed by using the modified Houkin’s grading system (MRA score).  Moyamoya vessels (MMVs) were evaluated by 2 grading systems: the MMV quality score and the MMV area score. Two  diagnostic criteria for MMD were used: the T2 criteria, which used flow voids in the basal ganglion on T2-weighted images, and the TOF criteria, which used the high-intensity areas in the basal ganglion on source images from TOF MRA. All  data were evaluated by 2 independent readers who were blinded to the strength field and presence or absence of MMD.  Using conventional angiography as the gold standard, the sensitivity and specificity of 7.0-T and 3.0-T MRI/MRA in the  diagnosis of MMD were calculated. The differences between 7.0-T and 3.0-T MRI and MRA were statistically compared.