Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases
Primary scattered multifocal melanocytomas in spinal canal mimicking neurofibromatosis.
First author：Chenlong Yang
Corresponding author：Yulun Xu
essential_information
- Person in charge：Chenlong Yang
- Data Sources： OTHERS
- Number of papers：OTHERS20190403
- Published time：2016-08-01
2016-08-01
Published articles
Journal：Spine J
Publication type: Case Report
IF(IF): 4.166
PMID: 26970601 Link To Pubmed Full text Download
Background And Purpose
Method
On admission, the cerebral magnetic resonance images of the patient were normal, whereas the spinal magnetic resonance images showed scattered multifocal nodules mimicking neurofibromatosis. Surgical resection of the responsible lesions was scheduled. In addition to this case presentation, relevant previous reports were reviewed, and the challenging diagnosis, management, and prognosis of meningeal melanocytoma are discussed
Conclusion
Clinicians should be alert to a potential aggressive clinical course of meningeal melanocytoma, despite its benign histopathological nature. Of particular note is multifocality and diffuse leptomeningeal hyperpigmentation, which may suggest a poor prognosis. A combined treatment including surgical resection and adjuvant radiotherapy should be considered, and long-term close follow-up is necessary.