Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases
essential_information
2016-04-01
Published articles
Journal：World Neurosurgery
Publication type: Research Article
IF(IF): 2.104
PMID: 26748171 Link To Pubmed Full text Download
Background And Purpose
Method
A consecutive series of 25 patients with primary spinal PNETs were enrolled. The diagnosis was cPNETs in 6 patients for negative CD99 expression and pPNETs in 19 patients for positive CD99 expression. Overall, gross total resection (GTR) was achieved in 12 patients, subtotal resection was conducted in 9 patients and partial resection was performed in 4 patients. Fourteen patients underwent postoperative chemotherapy and 16 patients underwent radiotherapy
Conclusion
Patients with spinal cPNETs had a younger age compared to pPNETs. The prognosis of spinal cPNETs and pPNETs are poor and there was no significant difference. The most beneficial treatment modality is GTR combined with adjuvant radiotherapy and chemotherapy.
Main results
There were 25 consecutive patients with primary spinal primitive neuroectodermal tumors enrolled. The diagnosis was cPNET in 6 patients with negative CD99 expression and pPNET in 19 patients with positive CD99 expression. Gross total resection (GTR) was achieved in 12 patients, subtotal resection was performed in 9 patients, and partial resection was performed in 4 patients. Postoperative chemotherapy was given to 14 patients, and radiotherapy was given to 16 patients.