国家神经系统疾病临床医学研究中心数据管理与共享系统

Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases

《国家中心数据管理与共享系统操作说明书 —— 研究者部分》

Spinal Intramedullary Syphilitic Gumma: An Unusual Presentation of Neurosyphilis.

第一作者：Chenlong Yang

通讯作者：Yulun Xu

Antibiotic; Intramedullary; Neurosyphilis; Spinal

基本信息

  • 负责人：Chenlong Yang
  • 数据来源： OTHERS
  • 论文编号：OTHERS20190452
  • 发表时间：2016-07-13

2016-07-13

已发表文章

发表杂志：World Neurosurgery

发表类型: Case Report

影响因子(IF): 2.104

PMID: 27452967 Pubmed原文链接 全文下载

主要研究背景及目的

方法

A 65-year-old woman with a history of neck, shoulder, and back pain presented with progressive sensorimotor disturbance of the extremities. Serologic tests revealed the presence of syphilis. Magnetic resonance imaging demonstrated an intramedullary nodule at the C5 level. A suspected diagnosis of spinal intramedullary tumor was made, and surgical resection of the nodule was performed. Histologic and immunohistochemical findings revealed a syphilitic gumma. We also conducted a comprehensive review of the published literature in all languages regarding spinal syphilitic gumma. The clinical and radiologic features, laboratory findings, therapeutic strategies, and follow-up data were analyzed.

结论

Spinal syphilitic gumma can occur in the intramedullary region, and clinicians should be aware of this extremely rare entity, as it can be easily mistaken for more common neoplasms occurring at this site. The magnetic resonance imaging appearance of this entity has some suggestive characteristics, and a confident diagnosis depends on the pathology. Surgical resection can help to relieve acute spinal cord compression, and systemic antibiotic treatment for syphilis should be emphasized for long-term control.

主要结果