Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases
Factors associated with perforator stroke after selective basilar artery angioplasty or stenting
First author：Jia, Baixue
Corresponding author：Miao, Zhongrong
essential_information
- Person in charge：Jia, Baixue
- Data Sources： OTHERS
- Number of papers：OTHERS20190500
- Published time：2017-08-01
2017-08-01
Published articles
Journal：J Neurointerv Surg
Publication type: Original Research
IF(IF): 5.836
PMID: 27387711 Link To Pubmed Full text Download
Background And Purpose
Method
Consecutive patients undergoing basilar artery angioplasty and/or stenting due to symptomatic atherosclerotic stenosis were retrospectively included in this single-center study. Analyzed variables including demographic data, risk factors of atherosclerosis, symptoms, characteristics of imaging, and procedure factors were extracted from electronic health records or imaging data. The main outcome was perforator stroke associated with the procedure. Multivariate analysis that correlated factors with the occurrence of perforator stroke in these patients was performed.
Conclusion
Diabetes, time from last symptom to procedure, and pre-procedure stenosis percentage may be factors affecting the risk of perforator stroke associated with basilar artery angioplasty and/or stenting. These factors should be considered in planning of potential basilar artery angioplasty and/or stenting and prospectively evaluated in future multicenter trials.
Main results
A total of 255 patients were included in the study. Perforator stroke associated with angioplasty and/or stenting was identified in 13 patients (5.1%). Variables with significant correlation with post-procedural perforator stroke included diabetes (OR 6.496; 95% CI 1.741 to 24.241; p=0.005), time from last symptom to procedure <18 days (OR 5.669; 95% CI 1.174 to 27.371; p=0.031), and pre-procedure stenosis percentage <88.4% (OR 5.882; 95% CI 1.465 to 23.608; p=0.012).