Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases
Risk factors of dilated Virchow-Robin spaces are different in various brain regions
First author：Zhang,Changqing,Chen, Qidong
Corresponding author：Wang, Yongjun
essential_information
- Person in charge：Zhang,Changqing,Chen, Qidong
- Data Sources： CICAS
- Number of papers：CICAS20150100
- Published time：2014-08-26
2014-08-26
Published articles
Background And Purpose
BACKGROUND AND PURPOSE: Few studies have reported on the risk factors of dilated Virchow-Robin Spaces (dVRS) in large samples of ischemic stroke patients. Little evidence exists regarding the relationship between dVRS and etiologic subtype of ischemic stroke or lacune. We aimed to investigate the risk factors associated with the severity of dVRS in a large sample of ischemic stroke patients. METHODS: We consecutively enrolled 1,090 patients who experienced an ischemic stroke within the past seven days and underwent a 3.0 T MRI scan in the Chinese IntraCranial AtheroSclerosis Study (ICAS). Clinical data and cranial MRI information of patients included age, sex, vascular risk factors, dVRS, leukoaraiosis, lacune, and etiologic subtype of ischemic stroke. Analyses were performed regarding the risk factors associated with the severity of dVRS by univariate analysis and multivariable ordinal logistic regression analysis.