国家神经系统疾病临床医学研究中心数据管理与共享系统
Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases
Brain Arteriovenous Malformations Located in Premotor Cortex: Surgical Outcomes and Risk Factors for Postoperative Neurologic Deficits
第一作者：Jiao, Yuming
通讯作者：Zhao, Jizong
基本信息
- 负责人：Jiao, Yuming
- 数据来源： OTHERS
- 论文编号：OTHERS20190548
- 发表时间：2017-09-01
2017-09-01
已发表文章
主要研究背景及目的
方法
We retrospectively reviewed patients with PMC-BAVMs who underwent surgical resection of the nidus. All patients had undergone preoperative functional magnetic resonance imaging, diffusion tensor imaging, magnetic resonance imaging, three-dimensional time-of-flight magnetic resonance angiography, and digital subtraction angiography. Functional and angioarchitectural factors were analyzed with respect to postoperative NDs. Function-related fiber tracts, corticospinal tract, and dominant arcuate fasciculus were tracked. Lesion-to-fiber distance was measured.
结论
Varying degrees of motor and language deficits can be induced immediately after resection of PMC-BAVMs. Permanent and long-term severe motor or language deficits are rare. Shorter lesion-to-eloquent fiber distance is a risk factor for short-term NDs. Larger nidus size is a risk factor for short-term and long-term NDs.
主要结果
We identified 36 patients with PMC-BAVMs. Radical resection was achieved in all patients. Four patients (11.1%) presented with limb-kinetic apraxia and bradykinesia. Short-term NDs developed in 12 (33.3%) patients, among which 6 developed aphasias and 7 developed muscle weakness. A shorter lesion-to-eloquent fiber distance (P = 0.012) and larger nidus size (P = 0.048) were significantly associated with short-term NDs. Long-term NDs occurred in 5 patients. Larger nidus size was significantly associated (P = 0.015) with long-term NDs.