Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases
Clinical Predictors of Diabetes Insipidus After Transcranial Surgery for Pituitary Adenoma
First author：Wang, Songquan Li, Deling
Corresponding author：Jia, Guijun
essential_information
- Person in charge：Wang, Songquan Li, Deling
- Data Sources： OTHERS
- Number of papers：OTHERS20190553
- Published time：2017-05-01
2017-05-01
Published articles
Journal：World Neurosurg
Publication type: Original Article
IF(IF): 2.104
PMID: 28153615 Link To Pubmed Full text Download
Background And Purpose
Method
The perioperative records of 90 patients who underwent transcranial (TC) surgery at the authors' institution between November 2011 and March 2013 were chosen from 1657 patients with pituitary adenoma and retrospectively analyzed. The degree of deformation of the third ventricle and hypothalamus were assessed by preoperative magnetic resonance imaging.
Conclusion
The degree of deformation of the third ventricle and hypothalamus assessed by preoperative magnetic resonance imaging may help to predict postoperative DI. Postoperative hemorrhage might increase the incidence of postoperative DI, whether it is immediate postoperative DI or permanent DI.
Main results
Immediate postoperative DI was found in 30 patients (33.3%). Persistent DI was noted in 11 patients (12.6%). Compared with patients in the nonpostoperative DI group, those with postoperative DI had a higher degree of deformation of the third ventricle and hypothalamus (P < 0.001). In a binary logistic regression analysis, the degree of deformation of the third ventricle and hypothalamus (odds ratio [OR], 3.079; 95% confidence interval [CI], 1.600-5.925; P = 0.001) had a significant positive correlation with immediate postoperative DI, as well as postoperative hemorrhage (OR, 6.235, 95% CI, 1.457-26.689; P = 0.014). Postoperative hemorrhage (OR, 4.363; 95% CI, 1.021-18.647; P = 0.047) showed a positive correlation with permanent DI, as well as the degree of deformation of the third ventricle and hypothalamus (OR, 2.336; 95% CI, 1.005-5.427; P = 0.049).