Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases
Glioma in Patients with Autosomal-Dominant Polycystic Kidney Disease
First author：Hao, Shuyu
Corresponding author：Gao, Zhixian
essential_information
- Person in charge：Hao, Shuyu
- Data Sources： OTHERS
- Number of papers：OTHERS20190560
- Published time：2017-02-01
2017-02-01
Published articles
Journal：World Neurosurgery
Publication type: Research Article
IF(IF): 2.104
PMID: 27565461 Link To Pubmed Full text Download
Background And Purpose
Method
We report 2 cases of glioma in patients with ADPKD. One patient had a cystic lesion with contrast enhancement in the right temporal lobe as revealed by magnetic resonance imaging and an aneurysm in left sylvian fissure confirmed by computed tomography angiography. Subsequent histopathologic analysis of the resected enhancing lesion confirmed the diagnosis of glioblastoma (World Health Organization grade IV). The second patient was found to harbor a solid lesion in the right parietal lobe. This lesion also proved to be an astrocytoma (World Health Organization grade II).
Conclusion
These 2 independent cases of glioma suggest an unusual clinical manifestation of ADPKD. The potential association between ADPKD and glioma pathogenesis should be further explored.
Main results
These 2 independent cases of glioma suggest an unusual clinical manifestation of ADPKD. The potential association between ADPKD and glioma pathogenesis should be further explored.