国家神经系统疾病临床医学研究中心数据管理与共享系统

Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases

Effect of clopidogrel with aspirin on functional outcome in TIA or minor stroke-——CHANCE substudy

第一作者:Xianwei Wang

通讯作者:Yongjun Wang,Yilong Wang

基本信息

  • 负责人:Xianwei Wang
  • 数据来源: CHANCE
  • 论文编号:CHANCE20150112
  • 发表时间:2015-08-18

2015-08-18

已发表文章

发表杂志:Neurology

发表类型: Original Contributions

影响因子(IF): 9.91

PMID: 26283758 Pubmed原文链接 全文下载

主要研究背景及目的

We compared the effect of clopidogrel plus aspirin vs aspirin alone on functional outcome and quality of life in the Clopidogrel in High-risk Patients with Acute Non-disabling Cerebrovascular Events (CHANCE) trial of aspirin-clopidogrel vs aspirin alone after acute minor stroke or TIA.

方法

Participants were assessed at 90 days for functional outcome using the modified Rankin Scale (mRS) and quality of life using the EuroQol-5 Dimension (EQ-5D). Poor functional outcome was defined as mRS score of 2–6 at 90 days and poor quality of life as EQ-5D index score of 0.5 or less.

结论

主要结果