Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases
Hemodynamic findings associated with intraoperative appearances of intracranial aneurysms
First author：Jiang Pengjun,Liu Qingyuan, Qingyuan
Corresponding author：Wang Shuo, Shuo
essential_information
- Person in charge：Jiang Pengjun,Liu Qingyuan, Qingyuan
- Data Sources： OTHERS
- Number of papers：OTHERS20190691
- Published time：2018-09-21
2018-09-21
Published articles
Background And Purpose
Method
Forty-one consecutive patients with unruptured middle cerebral artery (MCA) bifurcation aneurysms were included in our study. Based on the appearances observed under the microscope, aneurysms were classified into two different types: thick-walled and thin-walled aneurysms. Preoperative computed tomographic angiography (CTA) was used for geometry reconstruction and CFD analysis.
Conclusion
CFD may be a useful tool for discriminating the intraoperative appearance of cerebral aneurysms.
Main results
Morphological and hemodynamic parameters were compared between the two groups. Eighteen aneurysms were classified as thick-walled atherosclerotic ones according to their intraoperative appearances. Compared with thin-walled aneurysms, aneurysms with atherosclerotic changes had larger geometry parameters (aneurysm depth, maximum height, diameter, aspect ratio, size ratio), lower wall shear stress (WSS), and larger low WSS area ratio (LSAR). Thick-walled aneurysms characterized by atherosclerotic changes are associated with low WSS and larger LSAR