国家神经系统疾病临床医学研究中心数据管理与共享系统

Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases

《国家中心数据管理与共享系统操作说明书 —— 研究者部分》

Hemodynamic findings associated with intraoperative appearances of intracranial aneurysms

第一作者：Jiang Pengjun,Liu Qingyuan, Qingyuan

通讯作者：Wang Shuo, Shuo

基本信息

2018-09-21

已发表文章

发表杂志：Neurosurg Rev

发表类型: Article

影响因子(IF): 3.042

PMID: 30242546 Pubmed原文链接

主要研究背景及目的

方法

Forty-one consecutive patients with unruptured middle cerebral artery (MCA) bifurcation aneurysms were included in our study. Based on the appearances observed under the microscope, aneurysms were classified into two different types: thick-walled and thin-walled aneurysms. Preoperative computed tomographic angiography (CTA) was used for geometry reconstruction and CFD analysis.

结论

CFD may be a useful tool for discriminating the intraoperative appearance of cerebral aneurysms.

主要结果

Morphological and hemodynamic parameters were compared between the two groups. Eighteen aneurysms were classified as thick-walled atherosclerotic ones according to their intraoperative appearances. Compared with thin-walled aneurysms, aneurysms with atherosclerotic changes had larger geometry parameters (aneurysm depth, maximum height, diameter, aspect ratio, size ratio), lower wall shear stress (WSS), and larger low WSS area ratio (LSAR). Thick-walled aneurysms characterized by atherosclerotic changes are associated with low WSS and larger LSAR