国家神经系统疾病临床医学研究中心数据管理与共享系统

Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases

Intraosseous cavernous malformations of the skull: clinical characteristics and long-term surgical outcomes

第一作者:Wang Chengjun

通讯作者:Zhao Jizong

基本信息

  • 负责人:Wang Chengjun
  • 数据来源: OTHERS
  • 论文编号:OTHERS20190692
  • 发表时间:2018-10-17

2018-10-17

已发表文章

发表杂志:Neurosurg Rev

发表类型: Original Article

影响因子(IF): 3.042

PMID: 30327895 Pubmed原文链接 全文下载

主要研究背景及目的

方法

We performed a retrospective analysis of a series of 16 cranial ICM patients who underwent surgical treatment in our hospital between 2003 and 2016.

结论

Surgical resection should be the treatment of choice for the symptomatic patients and their long-term outcomes were excellent after gross total removal.

主要结果

The incidence of cranial ICM was 1.15% among the entire series of intracranial and intraspinal CMs. Our cohort included 6 male and 10 female patients; their mean age at operation was 38.7 years (range, 1.9 to 63 years). Slowly growing swelling was the commonest clinical manifestation of this disease. Complete lesion resection was achieved in all but one patient, and cranioplasty was performed using titanium mesh in 11 cases. Postoperative complication was found in one patient who developed diplopia, and this symptom resolved spontaneously before discharge. The mean follow-up period after operation was 76.2 months (range, 19 to 119 months). Only the patient with petroclival ICM had some occasional headaches (mRS = 1); others were all in stable neurological status (mRS = 0). No lesion recurrence was found during the follow-up period. Although cranial ICM is rare, it should always be considered as a differential diagnosis in the case of firm, gradually enlarging skull lesions.