Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases
Neurosurgical management of cavernous malformations located at the foramen of Monro
First author：Wang Chengjun
Corresponding author：Zhao Jizong
essential_information
- Person in charge：Wang Chengjun
- Data Sources： OTHERS
- Number of papers：OTHERS20190693
- Published time：2018-07-01
2018-07-01
Published articles
Journal：Neurosurg Rev
Publication type: Article
IF(IF): 3.042
PMID: 29199381 Link To Pubmed Full text Download
Background And Purpose
Method
We present a series of nine FM CM patients (four males, five females; mean age 29.3 years) who were treated at a single neurosurgical center.
Conclusion
FM CMs are rare and challenging lesions; they have a female predilection. The most common clinical manifestations of FM CM are the symptoms of mass effect. The seizure risk of FM CMs seems to be significantly lower than that of general intraventricular CMs. Early surgical intervention should be offered to symptomatic cases, and gross total resection is associated with favorable neurological outcomes.
Main results
FM CM accounted for 0.56% of the entire series of the central nervous system (CNS) CMs. Headache accompanied by nausea and vomiting was the most common initial symptom (55.6%). The mean preoperative Karnofsky Performance Scale (KPS) score was 84.4 (range 70-100). In all but one patient, the lesions were surgically resected. Postoperatively, two patients developed obstructive hydrocephalus, and one experienced motor aphasia and right hemiparesis. At the time of discharge, the KPS score improved to a mean of 88.9. Follow-up period after diagnosis was 18 to 131 months (mean 69.7 months); all the patients were considered to be in excellent clinical condition.