Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases

Risk Factors for Epilepsy Recurrence after Revascularization in Pediatric Patients with Moyamoya Disease

First author:Ma, Yonggang Zhao, Meng

Corresponding author:Zhao, Jizong

We identified the duration of epilepsy as an indep

essential_information

2018-03-01

Published articles

Journal:J Stroke Cerebrovasc Dis

Publication type: Article

IF(IF): 1.646

PMID: 29128331 Link To Pubmed

Background And Purpose

Method

Conclusion

We identified 28 pediatric patients with MMD who had seizures before revascularization. During follow-up (median 42 months), 7 patients (25.0%) experienced recurrent seizures. In the multivariate analysis, the duration of epilepsy was an independent predictor for postoperative seizure recurrences (odds ratio 3.84, 95% confidence interval 1.54-24.34; P?=?.035). The 2 common surgical modalities of MMD (direct and indirect bypass) had no significant difference in future seizure prevention in pediatric patients with MMD with epilepsy.

Main results

We reviewed 696 consecutive patients with MMD admitted to our hospital from 2009 to 2015. Pediatric patients with MMD who had seizures before revascularization were identified. We summarized the characteristics of seizures in pediatric patients with MMD and analyzed the predictive factors of recurrent seizure events.