国家神经系统疾病临床医学研究中心数据管理与共享系统

Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases

《国家中心数据管理与共享系统操作说明书 —— 研究者部分》

Risk Factors for Epilepsy Recurrence after Revascularization in Pediatric Patients with Moyamoya Disease

第一作者：Ma, Yonggang Zhao, Meng

通讯作者：Zhao, Jizong

We identified the duration of epilepsy as an indep

基本信息

2018-03-01

已发表文章

发表杂志：J Stroke Cerebrovasc Dis

发表类型: Article

影响因子(IF): 1.646

PMID: 29128331 Pubmed原文链接

主要研究背景及目的

方法

结论

We identified 28 pediatric patients with MMD who had seizures before revascularization. During follow-up (median 42 months), 7 patients (25.0%) experienced recurrent seizures. In the multivariate analysis, the duration of epilepsy was an independent predictor for postoperative seizure recurrences (odds ratio 3.84, 95% confidence interval 1.54-24.34; P?=?.035). The 2 common surgical modalities of MMD (direct and indirect bypass) had no significant difference in future seizure prevention in pediatric patients with MMD with epilepsy.

主要结果

We reviewed 696 consecutive patients with MMD admitted to our hospital from 2009 to 2015. Pediatric patients with MMD who had seizures before revascularization were identified. We summarized the characteristics of seizures in pediatric patients with MMD and analyzed the predictive factors of recurrent seizure events.