Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases
Anterior insular cortex plays a critical role in interoceptive attention
First author：Wang Xingchao,Wu Qiong
Corresponding author：Wu Yanhong,Gao Zhixian,Fan Jin
essential_information
- Person in charge：Wang Xingchao,Wu Qiong
- Data Sources： OTHERS
- Number of papers：OTHERS20190774
- Published time：2019-02-17
2019-02-17
Published articles
Background And Purpose
Method
Using a novel task that directs attention toward breathing rhythm, we assessed the involvement of the AIC in interoceptive attention in healthy participants using functional magnetic resonance imaging and examined the necessity of the AIC in interoceptive attention in patients with AIC lesions.
Conclusion
These results provide compelling evidence that the AIC plays a critical role in interoceptive attention.
Main results
Results showed that interoceptive attention was associated with increased AIC activation, as well as enhanced coupling between the AIC and somatosensory areas along with reduced coupling between the AIC and visual sensory areas. In addition, AIC activation was predictive of individual differences in interoceptive accuracy. Importantly, AIC lesion patients showed disrupted interoceptive discrimination accuracy and sensitivity.