Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases

The Third China National Stroke Registry (CNSR-III) for patients with acute ischaemic stroke or transient ischaemic attack: design, rationale and baseline patient characteristics

First author:Yongjun Wang

Corresponding author:Yongjun Wang

biomarker; outcome; registry; stroke; transient ischaemic attack

essential_information

  • Person in charge:Yongjun Wang
  • Data Sources: CNSR-Ⅲ
  • Number of papers:OTHERS20190879
  • Published time:2019-06-29

2019-06-29

Published articles

Journal:Stroke and vascular neurology

Publication type: Protocol

IF(IF): 4.081

PMID: 31709123 Link To Pubmed Full text Download

Background And Purpose

Method

Between August 2015 and March 2018, the CNSR-III recruited consecutive patients with ischaemic stroke or TIA from 201 hospitals that cover 22 provinces and four municipalities in China. Clinical data were collected prospectively using an electronic data capture system by face-to-face interviews. Patients were followed for clinical outcomes at 3 months, 6 months and 1–5 year annually. Brain imaging, including brain MRI and CT, were completed at baseline. Blood samples were collected and biomarkers were tested at baseline.

Conclusion

CNSR-III is a large scale nationwide registry in China. Data from this prospective registry may provide opportunity to evaluate imaging and biomarker prognostic determinants of stroke.

Main results

A total of 15 166 stroke patients were enrolled, among which 31.7% patients were women with the average age of 62.2±11.3 years. Ischaemic stroke was predominant (93.3%, n=14 146) and 1020 (6.7%) TIAs were enrolled.