国家神经系统疾病临床医学研究中心数据管理与共享系统

Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases

The Third China National Stroke Registry (CNSR-III) for patients with acute ischaemic stroke or transient ischaemic attack: design, rationale and baseline patient characteristics

第一作者:Yongjun Wang

通讯作者:Yongjun Wang

biomarker; outcome; registry; stroke; transient ischaemic attack

基本信息

  • 负责人:Yongjun Wang
  • 数据来源: CNSR-Ⅲ
  • 论文编号:OTHERS20190879
  • 发表时间:2019-06-29

2019-06-29

已发表文章

发表杂志:Stroke and vascular neurology

发表类型: Protocol

影响因子(IF): 4.081

PMID: 31709123 Pubmed原文链接 全文下载

主要研究背景及目的

方法

Between August 2015 and March 2018, the CNSR-III recruited consecutive patients with ischaemic stroke or TIA from 201 hospitals that cover 22 provinces and four municipalities in China. Clinical data were collected prospectively using an electronic data capture system by face-to-face interviews. Patients were followed for clinical outcomes at 3 months, 6 months and 1–5 year annually. Brain imaging, including brain MRI and CT, were completed at baseline. Blood samples were collected and biomarkers were tested at baseline.

结论

CNSR-III is a large scale nationwide registry in China. Data from this prospective registry may provide opportunity to evaluate imaging and biomarker prognostic determinants of stroke.

主要结果

A total of 15 166 stroke patients were enrolled, among which 31.7% patients were women with the average age of 62.2±11.3 years. Ischaemic stroke was predominant (93.3%, n=14 146) and 1020 (6.7%) TIAs were enrolled.