Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases
Relation between hypertension and erectile dysfunction: a meta-analysis of cross-section studies
First author：Wang Xiao-yan
Corresponding author：Zhang Yong
essential_information
- Person in charge：Wang Xiao-yan
- Data Sources： OTHERS
- Number of papers：OTHERS20190882
- Published time：2018-06-01
2018-06-01
Published articles
Journal：International Journal of Impotence Research
Publication type: Meta-analysis
IF(IF): 2.896
PMID: 29785046 Link To Pubmed Full text Download
Background And Purpose
Method
Sources included MEDLINE and EMBASE from 1966 to 2015. The reference lists of the retrieved studies were also investigated, and a meta-analysis were conducted. Eighteen cross-section studies involving a total of 41,943 participants and 10,151 cases of ED were used in this analysis.
Conclusion
The results of this meta-analysis support that hypertension is associated with an increased risk of ED. Further high-quality prospective studies are needed to confirm this observation.
Main results
We found that risk of ED was increased with hypertension (summary OR = 1.84, 95% CI: 1.58-2.14, p < 0.000001). Adjusting for obesity, unfavorable lipid levels, alcohol abuse, physical activity, cigarette smoking, educational level and other lifestyle factors, hypertension was also associated with increased risk of ED (summary OR = 1.58, 95% CI: 1.35-1.86, p < 0.00001).