国家神经系统疾病临床医学研究中心数据管理与共享系统

Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases

《国家中心数据管理与共享系统操作说明书 —— 研究者部分》

Totaled Health Risks in Vascular Events Score Predicts Clinical Outcome and Symptomatic Intracranial Hemorrhage in Chinese Patients After Thrombolysis

第一作者：Weiqi Chen,Yuesong Pan

通讯作者：Yongjun Wang,Yilong Wang

基本信息

2015-02-26

已发表文章

发表杂志：STROKE

发表类型: Brief Reports

影响因子(IF): 7.914

PMID: 25649799 Pubmed原文链接 全文下载

主要研究背景及目的

The performance of the Totaled Health Risks in Vascular Events (THRIVE) score in predicting clinical outcomes in Chinese patients with acute ischemic stroke post intravenous thrombolysis is unknown

方法

Data from the Thrombolysis Implementation and Monitor of Acute Ischemic Stroke in China (TIMS-China) study was used to compare the THRIVE score with other scores used to predict clinical outcomes and symptomatic intracranial hemorrhage after intravenous thrombolysis.

结论

The THRIVE score predicted reliably the risks of developing symptomatic intracranial hemorrhage, poor functional outcome, or death after intravenous thrombolysis therapy in Chinese patients with acute ischemic stroke. (Stroke. 2015;46:864-866. DOI: 10.1161/STROKEAHA.114.007979.)

主要结果

Among the 1128 patients with acute ischemic stroke who were included in this study, areas under the curve of the THRIVE score for symptomatic intracranial hemorrhage, 3-month poor functional outcomes, and death rate were 0.69, 0.71, and 0.78, respectively. The increased THRIVE score was related to the higher risk of developing symptomatic intracranial hemorrhage, poor functional outcomes, or death in patients with acute ischemic stroke at 3 months after thrombolysis.