Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases
Totaled Health Risks in Vascular Events Score Predicts Clinical Outcome and Symptomatic Intracranial Hemorrhage in Chinese Patients After Thrombolysis
First author：Weiqi Chen,Yuesong Pan
Corresponding author：Yongjun Wang,Yilong Wang
essential_information
- Person in charge：Weiqi Chen,Yuesong Pan
- Data Sources： TIMS-CHINA
- Number of papers：TIMS-CHINA20150136
- Published time：2015-02-26
2015-02-26
Published articles
Journal：STROKE
Publication type: Brief Reports
IF(IF): 7.914
PMID: 25649799 Link To Pubmed Full text Download
Background And Purpose
The performance of the Totaled Health Risks in Vascular Events (THRIVE) score in predicting clinical outcomes in Chinese patients with acute ischemic stroke post intravenous thrombolysis is unknown
Method
Data from the Thrombolysis Implementation and Monitor of Acute Ischemic Stroke in China (TIMS-China) study was used to compare the THRIVE score with other scores used to predict clinical outcomes and symptomatic intracranial hemorrhage after intravenous thrombolysis.
Conclusion
The THRIVE score predicted reliably the risks of developing symptomatic intracranial hemorrhage, poor functional outcome, or death after intravenous thrombolysis therapy in Chinese patients with acute ischemic stroke. (Stroke. 2015;46:864-866. DOI: 10.1161/STROKEAHA.114.007979.)
Main results
Among the 1128 patients with acute ischemic stroke who were included in this study, areas under the curve of the THRIVE score for symptomatic intracranial hemorrhage, 3-month poor functional outcomes, and death rate were 0.69, 0.71, and 0.78, respectively. The increased THRIVE score was related to the higher risk of developing symptomatic intracranial hemorrhage, poor functional outcomes, or death in patients with acute ischemic stroke at 3 months after thrombolysis.