国家神经系统疾病临床医学研究中心数据管理与共享系统

发表杂志：STROKE

发表类型: Original Contributions

影响因子(IF): 7.914

PMID: 34645284 Pubmed原文链接 全文下载

Malnutrition has been proven to have an adverse effect on the stroke patients. It is associated with increases in complications, mortality, and poor neurological outcomes in acute ischemic stroke patients. Screening patients with ischemic for malnutrition might identify patients at high risk of adverse outcomes who might benefit from tailored treatments or interventions to prevent deterioration and improve prognosis. Among malnutrition scores, the controlling nutritional status (CONUT) index, Triglycerides-total Cholesterol-Body weight-Index(TCBI), and the geriatric nutritional risk index (GNRI) have been studied in patients with cancer，

Study Population:CNSR-Ⅲ.The inclusion criteria are (1) older than 18 years old; (2) acute ischemic stroke,transient ischemic attack within 7 days of the index event;(3) informed consent provided by patients or legally authorized representatives. And we exclude patients who have no measurement of height, weight, laboratory parameters needed to calculate the index or follow-up recorded; we also excluded patients with a diagnosis of chronic lymphocytic leukemia. Statistical Analyses: The characteristics of all patients are reported as percentages for categorical variables, median (interquartile range) or mean (±standard deviation) for continuous variables. Statistical comparisons are appropriately carried out by the Pearson χ2 test, the Student t-test, or the Mann–Whitney U-test. Univariable and multivariable analyses with logistic regression are used to determine significant predictors of events. Receiver operating characteristic (ROC) curves are drawn for each model by plotting sensitivity versus one minus specificity. The power of each model to predict outcomes was calculated from the area under the ROC curve, the AUCs were compared using the z-test.