Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases
The PLAN score can predict poor outcomes of intracerebral hemorrhage
First author：Wanliang Du
Corresponding author：Yongjun Wang,Gaifen Liu
essential_information
- Person in charge：Wanliang Du
- Data Sources： CNSR-I
- Number of papers：CNSR-I20200046
- Published time：2020-01-01
2020-01-01
Published articles
Journal：Annals of Translational Medicine
Publication type: Original Contributions
IF(IF): 3.932
PMID: 32055605 Link To Pubmed Full text Download
Background And Purpose
For patients hospitalized after acute ischemic stroke (AIS), the preadmission comorbidities, level of consciousness (LOC), age and neurologic deficit (PLAN) score can help to identify those who may have a poor outcome. Implementing the PLAN score in other types of stroke may also have predictive value. Our study aimed to evaluate the PLAN score’s prognostic accuracy in predicting 1-year mortality and severe disability after intracerebral hemorrhage (ICH).
Method
We analyzed data found in the China National Stroke Registry (CNSR) of 2,453 hospitalized patients in 132 urban Chinese hospitals, diagnosed with ICH from September 2007 to August 2008. The outcomes analysis included 30-day mortality, modified Rankin Scale score (mRS) of 5–6 at discharge, and 1-year mortality. Univariate and multivariate analysis was performed, and we calculated consistency statistics (C statistic). We evaluated the PLAN score performance using area under the curve (AUC) calculations.
Conclusion
In patients hospitalized for ICH, the 30-day mortality, death or severe dependence at discharge and 1-year mortality can be predicted by the PLAN score. Similarly to patients hospitalized after AIS, the PLAN score can help to identify patients likely to have poor outcomes following hospitalization for ICH.
Main results
We found that the 30-day mortality was 12.6%, the frequency of a mRS 5–6 at discharge was 20.6%, and 1-year mortality was 21.9%. The PLAN score had good predictive value in 30-day mortality (C statistic, 0.82), death or severe dependence at discharge (0.84), and 1-year mortality (0.82).