国家神经系统疾病临床医学研究中心数据管理与共享系统

Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases

《国家中心数据管理与共享系统操作说明书 —— 研究者部分》

Predictors of post-thrombolysis symptomatic intracranial hemorrhage in Chinese patients with acute ischemic stroke

第一作者：Mingyong Liu, Yuesong Pan

通讯作者：Lichun Zhou, Yongjun Wang

symptomatic intracranial hemorrhage risk factor st

基本信息

2017-09-18

已发表文章

发表杂志：Plos ONE

发表类型: Original Contributions

影响因子(IF): 3.24

PMID: 28922363 Pubmed原文链接 全文下载

主要研究背景及目的

脑梗死溶栓后症状性脑出血是溶栓治疗的主要而且危险的并发症，不但影响患者预后而且会危及其生命。目前国内外对于溶栓后症状性脑出血的危险因素的认定尚不明确，本研究的目的在于寻找溶栓后症状性脑出血的危险因素，指导临床溶栓治疗。

方法

Data from the Thrombolysis Implementation and Monitor of Acute Ischemic Stroke in China (TIMS-China) study were assessed to explore risk factors for symptomatic intracranial hemorrhage after intravenous thrombolysis. Three candidate sICH definitions were analyzed.

结论

Cardioembolism, NIHSS on admission higher than 20, serum glucose on admission higher than 9.0 mmol/L and age ≧70 years were independent risk factors for symptomatic intracranial hemorrhage in Chinese patients with acute ischemic stroke treated with recombinant tissue plasminogen activator.

主要结果