Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases

《国家中心数据管理与共享系统操作说明书 —— 研究者部分》

Predictors of post-thrombolysis symptomatic intracranial hemorrhage in Chinese patients with acute ischemic stroke

First author：Mingyong Liu, Yuesong Pan

Corresponding author：Lichun Zhou, Yongjun Wang

symptomatic intracranial hemorrhage risk factor st

essential_information

2017-09-18

Published articles

Journal：Plos ONE

Publication type: Original Contributions

IF(IF): 3.24

PMID: 28922363 Link To Pubmed Full text Download

Background And Purpose

脑梗死溶栓后症状性脑出血是溶栓治疗的主要而且危险的并发症，不但影响患者预后而且会危及其生命。目前国内外对于溶栓后症状性脑出血的危险因素的认定尚不明确，本研究的目的在于寻找溶栓后症状性脑出血的危险因素，指导临床溶栓治疗。

Method

Data from the Thrombolysis Implementation and Monitor of Acute Ischemic Stroke in China (TIMS-China) study were assessed to explore risk factors for symptomatic intracranial hemorrhage after intravenous thrombolysis. Three candidate sICH definitions were analyzed.

Conclusion

Cardioembolism, NIHSS on admission higher than 20, serum glucose on admission higher than 9.0 mmol/L and age ≧70 years were independent risk factors for symptomatic intracranial hemorrhage in Chinese patients with acute ischemic stroke treated with recombinant tissue plasminogen activator.

Main results