国家神经系统疾病临床医学研究中心数据管理与共享系统

Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases

《国家中心数据管理与共享系统操作说明书 —— 研究者部分》

C-Reaction Protein and the Severity of Intracerebral Hemorrhage: A Study from Chinese Stroke Center Alliance

第一作者：Dandan Wang,Jing Wang

通讯作者：Yongjun Wang,Xingquan Zhao

intracerebral hemorrhage C-reaction protein outcome severity

基本信息

2021-09-24

已发表文章

发表杂志：Neurological Research

发表类型: Original Contributions

影响因子(IF): 2.448

PMID: 34559025 Pubmed原文链接 全文下载

主要研究背景及目的

Intracerebral hemorrhage (ICH) has a high mortality and morbidity in the world. C-reaction protein (CRP) and neutrophil to lymphocyte ratio (NLR) have been demonstrated to be the independent risk factors of some cardiovascular diseases. In our study, we aimed to find out the relationship between CRP and NLR levels and the severity of patients with ICH.

方法

This is a cross sectional study. Patients' basic characteristics and laboratory examination results, including the concentration of CRP, white blood cell, neutrophil and lymphocyte were taken. Chi- square test and logistic regression were used to analyze the relationship between these inflammation markers and clinical severity of ICH.

结论

High CRP level was independently associated with poorer clinical outcome and higher in-hospital death in patients with ICH.

主要结果