Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases

《国家中心数据管理与共享系统操作说明书 —— 研究者部分》

C-Reaction Protein and the Severity of Intracerebral Hemorrhage: A Study from Chinese Stroke Center Alliance

First author：Dandan Wang,Jing Wang

Corresponding author：Yongjun Wang,Xingquan Zhao

intracerebral hemorrhage C-reaction protein outcome severity

essential_information

2021-09-24

Published articles

Journal：Neurological Research

Publication type: Original Contributions

IF(IF): 2.448

PMID: 34559025 Link To Pubmed Full text Download

Background And Purpose

Intracerebral hemorrhage (ICH) has a high mortality and morbidity in the world. C-reaction protein (CRP) and neutrophil to lymphocyte ratio (NLR) have been demonstrated to be the independent risk factors of some cardiovascular diseases. In our study, we aimed to find out the relationship between CRP and NLR levels and the severity of patients with ICH.

Method

This is a cross sectional study. Patients' basic characteristics and laboratory examination results, including the concentration of CRP, white blood cell, neutrophil and lymphocyte were taken. Chi- square test and logistic regression were used to analyze the relationship between these inflammation markers and clinical severity of ICH.

Conclusion

High CRP level was independently associated with poorer clinical outcome and higher in-hospital death in patients with ICH.

Main results