Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases
PolyvasculaR Evaluation for Cognitive Impairment and vaScular Events (PRECISE)- a population-based prospective cohort study: rationale, design and baseline participant characteristics
First author：Yuesong Pan ,Jing Jing, Xueli Cai
Corresponding author：Tiemin Wei, Yongjun Wang
essential_information
- Person in charge：Yuesong Pan ,Jing Jing, Xueli Cai
- Data Sources： PRECISE
- Number of papers：OTHERS20200245
- Published time：2020-09-09
2020-09-09
Published articles
Journal：Stroke Vasc Neurol
Publication type: Study Protocol
IF(IF): 4.081
PMID: 32863279 Link To Pubmed Full text Download
Background And Purpose
Cardiovascular diseases and dementia are two major diseases in the elderly. Atherosclerosis is associated with future vascular events and cognitive impairment.
Method
Between May 2017 and September 2019, the PRECISE study enrolled 3067 community-dwelling adults with ages between 50 and 75 years cluster sampled from six villages and four communities of Lishui city in China. Data are collected in face-to-face interviews at baseline, 2-year and 4-year follow-up visits. Brain MRI including high-resolution sequences for intracranial and carotidal arteries and CT angiography for thoracoabdominal arteries were performed at baseline and will be rescanned after 4 years.
Conclusion
The PRECISE study is a population-based prospective cohort study with comprehensive evaluation of atherosclerotic stenosis and plaque using advanced vascular imaging techniques.
Main results
A total of 3067 subjects were enrolled, among which 53.5% were female with an average age of 61.2±6.7 years. Among them, 2.8%, 8.1%, 43.1% and 21.6% had a history of stroke, coronary heart diseases, hypertension and diabetes mellitus, respectively.