Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases
Joint associations of short-term exposure to gaseous air pollutants with hospital admission of ischemic stroke
First author：Tao Liu,Yong Jiang
Corresponding author：Wenjun Ma,Yongjun Wang
essential_information
- Person in charge：Tao Liu,Yong Jiang
- Data Sources： CSCA
- Number of papers：CSCA20220046
- Published time：
Published articles
Journal：
Publication type: Original Contributions
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Background And Purpose
Although numerous studies have estimated the associations of short-term exposure to particulate matter pollutants with incidence of ischemic stroke (IS), less studies focused on gaseous pollutants, and the joint associations of IS with gaseous pollution as a mixture remain unknown.We aim to investigate the individual and joint associations of short-term exposure to gaseous air pollutants with hospital admission for IS.
Method
A time-stratified case-crossover study was employed to investigate 824,808 IS patients in 292 Chinese cities from 2015 to 2019. Mean concentrations of maximum eight-hour average for O3 (O3-8h), nitrogen dioxide (NO2), sulfur dioxide (SO2), and carbon monoxide (CO) on each of the case and control days across all monitoring stations in the city where the IS patients resided were assessed. Conditional logistic regression models were conducted to estimate the exposure-response associations.