国家神经系统疾病临床医学研究中心数据管理与共享系统
Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases
Validation of the mSOAR and SOAR scores to predict early mortality in Chinese acute stroke patients
第一作者：Hui Wang
通讯作者：Yuesong Pan
2017-07-06
已发表文章
主要研究背景及目的
It is unclear in Chinese patients with acute stroke how the SOAR (stroke subtype, Oxfordshire Community Stroke Project classification, age, and prestrike modified Rankin) and mSOAR (modified-SOAR) scores performed in predicting discharge mortality and 3-month mortality. We aimed to validate the predictability of these scores in this cohort.
方法
Data from the China National Stroke Registry (CNSR) study was used to perform the mSOAR and SOAR scores for predicting the discharge and 3-month mortality in acute stroke patients.
结论
The mSOAR score predicted reliably the risk of death in Chinese acute stroke patients.
主要结果
A total of 11073 acute stroke patients were included in present study. The increased mSOAR and SOAR scores were closely related to higher death risk in acute stroke patients. For discharge mortality, the area under the receiver-operator curve (AUC) of the mSOAR and SOAR scores were 0.784 (95% CI 0.761–0.807) and 0.722 (95% CI: 0.698–0.746). For 3-month mortality, they were 0.787 (95% CI: 0.771–0.803) and 0.704 (95% CI: 0.687–0.721), respectively. The mSOAR and SOAR scores showed significant correlation between the predicted and observed probabilities of discharge mortality (mSOAR: r = 0.945, P = 0.001; SOAR: r = 0.994, P<0.001) and 3-month mortality (mSOAR: r = 0.984, P<0.001; SOAR: r = 0.999; P<0.001).