Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases
Validation of the mSOAR and SOAR scores to predict early mortality in Chinese acute stroke patients
First author：Hui Wang
Corresponding author：Yuesong Pan
essential_information
2017-07-06
Published articles
Journal：plos one
Publication type: Original Contributions
IF(IF): 3.24
PMID: 0180444 Link To Pubmed Full text Download
Background And Purpose
It is unclear in Chinese patients with acute stroke how the SOAR (stroke subtype, Oxfordshire Community Stroke Project classification, age, and prestrike modified Rankin) and mSOAR (modified-SOAR) scores performed in predicting discharge mortality and 3-month mortality. We aimed to validate the predictability of these scores in this cohort.
Method
Data from the China National Stroke Registry (CNSR) study was used to perform the mSOAR and SOAR scores for predicting the discharge and 3-month mortality in acute stroke patients.
Conclusion
The mSOAR score predicted reliably the risk of death in Chinese acute stroke patients.
Main results
A total of 11073 acute stroke patients were included in present study. The increased mSOAR and SOAR scores were closely related to higher death risk in acute stroke patients. For discharge mortality, the area under the receiver-operator curve (AUC) of the mSOAR and SOAR scores were 0.784 (95% CI 0.761–0.807) and 0.722 (95% CI: 0.698–0.746). For 3-month mortality, they were 0.787 (95% CI: 0.771–0.803) and 0.704 (95% CI: 0.687–0.721), respectively. The mSOAR and SOAR scores showed significant correlation between the predicted and observed probabilities of discharge mortality (mSOAR: r = 0.945, P = 0.001; SOAR: r = 0.994, P<0.001) and 3-month mortality (mSOAR: r = 0.984, P<0.001; SOAR: r = 0.999; P<0.001).