国家神经系统疾病临床医学研究中心数据管理与共享系统
Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases
Jugular Venous Reflux Is Associated with Perihematomal Edema after Intracerebral Hemorrhage
第一作者：Hao Feng
2017-06-16
已发表文章
发表杂志：BioMed Research International
发表类型: Original Contributions
影响因子(IF): 3.411
PMID: 28691032 Pubmed原文链接 全文下载
主要研究背景及目的
The purpose of this study was to determine whether jugular venous reflux (JVR) is associated with perihematomal edema (PHE) in individuals with intracerebral hemorrhage (ICH).
方法
Patients with spontaneous supratentorial ICH within 72 h of symptom onset were enrolled. Baseline brain computed tomography (CT) scan was performed, with a follow-up CT examination at 12 ± 3 days after onset. Jugular venous color Doppler ultrasound was performed at 12 ± 3 days after onset to examine the JVR status.
结论
JVR is associated with both absolute and relative PHE volumes after ICH.
主要结果
A total of 65 patients with ICH were enrolled. In logistic regression analysis, absolute PHE volume was significantly associated with JVR (OR, 5.46; 95% CI, 1.04-28.63; p = 0.044) and baseline hematoma volume (OR, 1.14; 95% CI, 1.03-1.26; p = 0.009) within 72 h of onset. It was also correlated with JVR (OR, 15.32; 95% CI, 2.52-92.99; p = 0.003) and baseline hematoma volume (OR, 1.14; 95% CI, 1.04-1.24; p = 0.006) at 12 ± 3 days after onset. In a similar manner, relative PHE volume was significantly associated with JVR (OR, 14.85; 95% CI, 3.28-67.17; p < 0.001) within 72 h of onset and at 12 ± 3 days after onset (OR, 5.87; 95% CI, 1.94-17.77; p = 0.002).