Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases
Jugular Venous Reflux Is Associated with Perihematomal Edema after Intracerebral Hemorrhage
First author：Hao Feng
Corresponding author：Xingquan Zhao,Jian Zhou
essential_information
2017-06-16
Published articles
Journal：BioMed Research International
Publication type: Original Contributions
IF(IF): 3.411
PMID: 28691032 Link To Pubmed Full text Download
Background And Purpose
The purpose of this study was to determine whether jugular venous reflux (JVR) is associated with perihematomal edema (PHE) in individuals with intracerebral hemorrhage (ICH).
Method
Patients with spontaneous supratentorial ICH within 72 h of symptom onset were enrolled. Baseline brain computed tomography (CT) scan was performed, with a follow-up CT examination at 12 ± 3 days after onset. Jugular venous color Doppler ultrasound was performed at 12 ± 3 days after onset to examine the JVR status.
Conclusion
JVR is associated with both absolute and relative PHE volumes after ICH.
Main results
A total of 65 patients with ICH were enrolled. In logistic regression analysis, absolute PHE volume was significantly associated with JVR (OR, 5.46; 95% CI, 1.04-28.63; p = 0.044) and baseline hematoma volume (OR, 1.14; 95% CI, 1.03-1.26; p = 0.009) within 72 h of onset. It was also correlated with JVR (OR, 15.32; 95% CI, 2.52-92.99; p = 0.003) and baseline hematoma volume (OR, 1.14; 95% CI, 1.04-1.24; p = 0.006) at 12 ± 3 days after onset. In a similar manner, relative PHE volume was significantly associated with JVR (OR, 14.85; 95% CI, 3.28-67.17; p < 0.001) within 72 h of onset and at 12 ± 3 days after onset (OR, 5.87; 95% CI, 1.94-17.77; p = 0.002).