Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases
The Disability Rate of 5-Year Post-Stroke and Its Correlation Factors: A National Survey in China
First author：yangyang
Corresponding author：Chunxue Wang,Yutao Xiang
essential_information
2016-11-08
Published articles
Journal：plos one
Publication type: Original Contributions
IF(IF): 3.24
PMID: PMC5100878 Link To Pubmed Full text Download
Background And Purpose
Few studies on long-term functional outcome have been conducted in post-stroke patients in China. The objective of this study was to conduct a nationwide survey in China to investigate the 5-year prevalence of post-stroke disability and its correlation factors
Method
A total of 893 patients with ischemic stroke were included. Demographic, clinical and neuro-imaging information were collected with standardized instruments that assessed stroke severity,depression, cognitive impairment, stroke recurrence and physical disability. Disability was assessed with the modified Ranking Score (mRS), of which a cutoff score 2 indicates disability. Statistical analysis included chi-square tests, two independent samples t-tests, Mann-Whitney U test and multiple logistic regression analysis.
Conclusion
The disability rate in 5-year post-stroke was high in Chinese patients. Treatment of depression, secondary prevention of stroke and rehabilitation may benefit disabled patients with stroke in China
Main results
The frequency of disability in this study population was 45%. Multivariate analyses revealed that older age, lower education level, previous history of stroke, stroke severity at admission, depression, cognitive impairment at 3 months, and stroke recurrence within 5 years follow up were all significantly associated with post-stroke disability.