国家神经系统疾病临床医学研究中心数据管理与共享系统
Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases
2018-06-30
已发表文章
主要研究背景及目的
During the past several decades, stroke care delivery has transformed from experience-based to evidence-based practice. The rapid development of thrombolysis, endovascular therapy, and secondary prevention treatment has led to an increase in the number of clinical research studies and thus, this article will focus on the opportunities, advantages, challenges, and potential pitfalls of becoming a local PI for a large multicenter clinical trial.
方法
Clinical trials with multiple sites are necessary for studying large samples of patients to determine what therapeutic, preventative, and diagnostic products or interventions are best across multiple settings and will be effective in actual practice. Each participating site needs a local principal investigator (PI) whose guide the early career stroke physicians and researchers.
结论
Open communication and mentoring, locally and as part of the clinical trials infrastructure, should be developed for early career site PIs to succeed in their important role in the advancement of clinical stroke research.
主要结果
The growing number and complexity of stroke clinical trials provide early career stroke physicians with opportunities for leadership, scholarship, and partnership as site PI for multicenter clinical trials.