Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases
essential_information
2014-12-01
Published articles
Journal：The Spine Journal
Publication type: Case Report
IF(IF): 3.196
PMID: 25088958 Link To Pubmed Full text Download
Background And Purpose
Method
The patient underwent a C5–C6 laminotomy, and total resection was achieved. A histopathologic examination revealed that the mass was consistent with a diagnosis of Rosai-Dorfman disease (RDD) (Fig. 2). During 18 months of follow-up, the man remained symptom free, and no evidence of ecurrence was found on MRI examination.
Conclusion
RDD should be included in the differential diagnosis of intraspinal dural-based lesions, even without lymphadenopathy and associated systematic changes.
Main results
Rosai-Dorfman disease is a rare definitive histiocytic disorder,characterized by massive painless ervical lymphadenopathy variably associated with fever, leukocytosis,elevated erythrocyte sedimentation rate, hypergammaglobulinemia,and weight loss [1]. Various extranodal localizations have been described, and spinal involvement in RDD causing spinal cord compression is extremely rare [2]. The lesion is commonly attached to the dura mater, which can show dura tail sign and radiologically resemble meningiomas.