国家神经系统疾病临床医学研究中心数据管理与共享系统
Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases
Long-term temozolomide might be an optimal choice for patient with multifocal glioblastoma, especially with deep-seated structure involvement: a case report and literature review
第一作者：Yunpeng Liu
通讯作者：Zhixian Gao
基本信息
- 负责人：Yunpeng Liu
- 数据来源： OTHERS
- 论文编号：OTHERS20190341
- 发表时间：2015-04-09
2015-04-09
已发表文章
发表杂志：World Journal of Surgical Oncology
发表类型: Case Report
影响因子(IF): 2.754
PMID: 25889578 Pubmed原文链接 全文下载
主要研究背景及目的
方法
Multifocal glioblastoma is an uncommon and refractory subtype of high-grade glioma since the burden of masses could not be eliminated simply by operation, and it is getting even harder to control if some deep structures, like thalamus and pineal region, are involved.
结论
Long-term temozolomide might be an optimal choice for patients with multifocal glioblastoma, especially with deep-seated structure involvement.
主要结果
Here we report a case of a 30-year-old male with multifocal glioblastoma affected his right thalamus, left lateral ventricle, and pineal region. Clinical manifestations include operation, concurrent radiochemotherapy, and a 12-cycle adjuvant temozolomide administration. The masses of this patient nearly disappeared after 15 months from the primary diagnosis, and no severe adverse event or neurological sequel occurred.