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Long-term temozolomide might be an optimal choice for patient with multifocal glioblastoma, especially with deep-seated structure involvement: a case report and literature review
First author：Yunpeng Liu
Corresponding author：Zhixian Gao
essential_information
- Person in charge：Yunpeng Liu
- Data Sources： OTHERS
- Number of papers：OTHERS20190341
- Published time：2015-04-09
2015-04-09
Published articles
Journal：World Journal of Surgical Oncology
Publication type: Case Report
IF(IF): 2.754
PMID: 25889578 Link To Pubmed Full text Download
Background And Purpose
Method
Multifocal glioblastoma is an uncommon and refractory subtype of high-grade glioma since the burden of masses could not be eliminated simply by operation, and it is getting even harder to control if some deep structures, like thalamus and pineal region, are involved.
Conclusion
Long-term temozolomide might be an optimal choice for patients with multifocal glioblastoma, especially with deep-seated structure involvement.
Main results
Here we report a case of a 30-year-old male with multifocal glioblastoma affected his right thalamus, left lateral ventricle, and pineal region. Clinical manifestations include operation, concurrent radiochemotherapy, and a 12-cycle adjuvant temozolomide administration. The masses of this patient nearly disappeared after 15 months from the primary diagnosis, and no severe adverse event or neurological sequel occurred.