国家神经系统疾病临床医学研究中心数据管理与共享系统
Data Management And Sharing System of China National Clinical Research Center for Neurological Diseases
Chiari malformation type 1.5 in male monozygotic twins: case report and literature review
第一作者：Xiaofeng Deng
通讯作者：Yulun Xu
基本信息
- 负责人：Xiaofeng Deng
- 数据来源： OTHERS
- 论文编号：OTHERS20190354
- 发表时间：2015-03-01
2015-03-01
已发表文章
发表杂志：Clin Neurol Neurosurg
发表类型: Case Report And Literature Review
影响因子(IF): 1.672
PMID: 25621711 Pubmed原文链接 全文下载
主要研究背景及目的
方法
Monozygotic twins both with Chiari malformation are extremely rare. Chiari malformation type 1.5 has not been reported in monozygotic twins. The twins developed different symptoms at different ages, with nine years apart.
结论
This is the first report that describes CM 1.5 in monozygotic twins. The two identical twins and their different clinical presentations suggest that there may be a mix of both genetic and acquired factors playing a role in the development of Chiari malformation. Early operation should be emphasized, and an aggressive surgical strategy could be considered in the treatment of CM 1.5.
主要结果
This is the first report that describes CM 1.5 in monozygotic twins. The two identical twins and their different clinical presentations suggest that there may be a mix of both genetic and acquired factors playing a role in the development of Chiari malformation. Early operation should be emphasized, and an aggressive surgical strategy could be considered in the treatment of CM 1.5.