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Chiari malformation type 1.5 in male monozygotic twins: case report and literature review
First author：Xiaofeng Deng
Corresponding author：Yulun Xu
essential_information
- Person in charge：Xiaofeng Deng
- Data Sources： OTHERS
- Number of papers：OTHERS20190354
- Published time：2015-03-01
2015-03-01
Published articles
Journal：Clin Neurol Neurosurg
Publication type: Case Report And Literature Review
IF(IF): 1.672
PMID: 25621711 Link To Pubmed Full text Download
Background And Purpose
Method
Monozygotic twins both with Chiari malformation are extremely rare. Chiari malformation type 1.5 has not been reported in monozygotic twins. The twins developed different symptoms at different ages, with nine years apart.
Conclusion
This is the first report that describes CM 1.5 in monozygotic twins. The two identical twins and their different clinical presentations suggest that there may be a mix of both genetic and acquired factors playing a role in the development of Chiari malformation. Early operation should be emphasized, and an aggressive surgical strategy could be considered in the treatment of CM 1.5.
Main results
This is the first report that describes CM 1.5 in monozygotic twins. The two identical twins and their different clinical presentations suggest that there may be a mix of both genetic and acquired factors playing a role in the development of Chiari malformation. Early operation should be emphasized, and an aggressive surgical strategy could be considered in the treatment of CM 1.5.